Daily Mail reports that Parma Bertoli, 59, and partner Stephanie Nickles, 43, started a relationship back in 2004 when they were still men.
Stephanie underwent a full sex change in 2006 after having the procedure funded by the NHS while Parma went under the knife to become a woman in 2008
The couple, who live in Warndon, Worcester, had their birth certificates changed to reflect their new female identities.
Next month the couple are preparing to don white dresses for their wedding.
However, the couple have been forced to bring the big day forward after Parma was diagnosed with a terminal brain tumour last October and was given less than 12 months to live.
Parma, a former meat hygiene inspector, said: ‘Steph and I got together when we were both men in 2004 and lived together as men.
‘Steph was in pre-op so was living as a woman and I made the change soon after.couple2
‘Today we are still in love as women.
‘To us, gender is not an issue in our relationship. We are just two people who met and tried to help each other along.
‘I know I have a very limited amount of time left but it would mean the world to both of us to get married – it would be absolutely brilliant.’
The couple, who are hoping to get hitched at Worcester registry office next month, are now appealing for help and donations to make their dream wedding come true.
Parma added: ‘My fiancée has always wanted a special occasion and we are really having to bring it forward because my situation is quite bad.
‘I am very lucky to have got this far through the support of my partner.’