He also mentioned that he believes playmaker Dani Olmo will be available to play, despite experiencing some illness overnight.
Additionally, defender Pau Cubarsi is expected to participate in the match, even after sustaining a facial cut during the team's Champions League victory over Red Star Belgrade on Wednesday.
“Pau, I think (he will be fit), he trained with us for the whole training session,” Flick told reporters.
“Lamine, he was (working) inside and did specific strength training. He’s had a lot of matches in the last weeks so we took care of him… we’ll see what the situation is tomorrow.
“With Dani he felt a little bit uncomfortable at night and this morning is doing better, so with him just treatments and medical things, I think he’s ready for tomorrow.”
Barcelona entered the weekend with a nine-point advantage over second-placed Real Madrid. Flick also highlighted the significance of punctuality for his players.
According to Spanish media, French defender Jules Kounde was excluded from the starting lineup against Alaves in October due to his late arrival at a team meeting.
“It’s a rule. I don’t speak about what happened in the past, it’s just about respect for the team,” said Flick.
“If you are five minutes too late, the others have to wait, this is not respect, this is not my understanding of being respectful.”