Liverpool and Ajax extended their perfect winning records in the Champions League on Wednesday to advance into the round of 16. Liverpool cruised past Spanish champions Atletico Madrid 2-0 at Anfield and Ajax hit 10-man Borussia Dortmund with late goals in a 3-1 come-from-behind win in Germany.

The four teams with four straight wins - after Bayern Munich and Juventus sealed their places Tuesday - have already given the knockout lineup a nostalgic feel. Ajax, Bayern and Liverpool combined to win all eight European Cup titles from 1971-78.

Liverpool had never opened a Champions League group stage with four wins, though they were rarely troubled against Atletico in Group B after Diogo Jota and Sadio Mané scored in the first 21 minutes. Atletico dropped to third in the group behind Porto, who were held to a 1-1 draw at last-place AC Milan.

Ajax are having a standout Champions League campaign after being ignored by the Super League founders from England, Italy and Spain when they lined up their ill-fated project several months ago.

The Dutch champions made it back-to-back big wins over Dortmund, which had veteran defender Mats Hummels sent off in the first half.

Second-place Dortmund trail Ajax by six points in Group C with two rounds left. Dortmund are level on points with Sporting Lisbon, who routed Besiktas 4-0 and host the German side next on November 24.

Real Madrid and Inter Milan - two of the 12 Super League clubs - have taken control of Group D from upstart Sheriff after important wins on Wednesday.

Karim Benzema's goals ensured Madrid beat Shakhtar Donetsk 2-1 and lead the standings by two points from Inter. The Italian champions made it two straight wins over Sheriff, 3-1 away to the champions of Moldova.

Manchester City overpowered Club Brugge 4-1 and were rewarded with the top spot in Group A after late drama at Leipzig where Paris Saint-Germain drew 2-2.

A PSG team missing the injured Lionel Messi rallied from an early Leipzig surge to lead at halftime through two goals by Georgino Wijnaldum. But PSG dropped points after a stoppage-time penalty by Leipzig substitute Dominik Szoboszlai.

City took a one-point lead over PSG before they meet in Manchester in three weeks' time.