Children ages 1-9 in London were made eligible for booster doses of a polio vaccine Wednesday after British health authorities reported finding evidence the virus has spread in multiple areas of the city but found no cases of the paralytic disease in people.
Britain’s Health Security Agency said it detected viruses
derived from the oral polio vaccine in the sewage water of eight London
boroughs. The agency’s analysis of the virus samples suggested “transmission
has gone beyond a close network of a few individuals.”
The agency said it had not located anyone infected with the
virus and that the risk to the wider population was low. The decision to offer
young children boosters was a precaution, it said.
“This will ensure a high level of protection from paralysis
and help reduce further spread,” the agency said.
The agency said it is also expanding surveillance of sewage
water to at least another 25 sites in London and nationally.
Most people across Britain are vaccinated against polio in
childhood. According to the World Health Organization, only one in 200 polio
infections leads to paralysis; most people don’t show any symptoms.
The Health Security Agency said it was working closely with
health authorities at WHO and in the United States and Israel to investigate
any links to polio viruses detected in those two countries.
Kathleen O’Reilly, a polio expert at the London School of
Hygiene and Tropical Medicine, said the polio virus circulating in London was
“genetically related” to recent cases identified in the U.S. and Israel.
“Further investigation is needed to fully understand how
they are connected, but it does illustrate that this virus has the potential to
cause disease,” O’Reilly said in a statement.
Polio is a disease often spread in water that mostly affects
children under 5. It has mostly been wiped out from developed countries, but
outbreaks remain in Pakistan, Afghanistan and parts of Africa.
Initial symptoms include fever, fatigue, headache, vomiting,
and muscle stiffness. Among people paralyzed by the disease, death can occur in
up to 10% of cases when their breathing muscles become paralyzed.
In rare cases, the live virus contained in the oral polio
vaccine used in the global effort to eradicate the disease can mutate into new
forms potent enough to trigger new outbreaks. The vaccination booster effort in
London will use injected polio vaccines that do not carry that risk.
“We know the areas in London where the polio virus is being
transmitted have some of the lowest vaccination rates,” Dr. Vanessa Saliba, a
Health Security Agency epidemiologist, said.