Lady Gaga unveiled her latest single, “Disease,” an electro-pop track centered on healing a partner's “tortured” affliction, on Thursday evening. The lively song was co-written by Michael Polansky, Gaga, Andrew Watt, and Cirkut, with the latter three also serving as producers.

“Disease” marks the first release from Gaga’s upcoming seventh studio album, which she initially hinted at in July and confirmed in September, coinciding with the launch of “Joker: Folie à Deux.” The new album is scheduled for release in the spring of 2025, as stated in a press announcement.

In the song, Gaga expresses, “I could play the doctor / I can cure your disease. / If you were a sinner / I could make you believe / Lay you don’t like 1, 2, 3 / Eyes roll back in ecstasy / I can smell your sickness / I can cure ya / Cure your disease.”

In a conversation with Vogue, Gaga shared her thoughts on the new album, stating, “I feel like this new album, in a lot of ways, is about that time but from a place of happiness instead of misery.”

Recently, Gaga starred in “Joker: Folie à Deux,” which received mixed reviews and did not perform well at the box office. She also released a surprise companion album titled “Harlequin,” inspired by her character in the film. This album features mostly classic American Songbook standards, including “Get Happy,” “That’s Life,” and “That’s Entertainment,” along with a couple of original tracks. “Harlequin” debuted at No. 20 on the overall Billboard 200 chart.

Additionally, her collaboration with Bruno Mars, “Die With a Smile,” continues to excel on the Billboard Global 200 singles chart, maintaining its position as one of the longest-running No. 1 hits of the year.

Gaga's previous full-length album, “Chromatica,” released in 2020, became her sixth No. 1 album on the Billboard 200. It featured the hit singles “Stupid Love” and “Rain on Me” with Ariana Grande. Gaga supported the album with a tour, which was later released as a film on Max. Hints about her seventh album were included at the end of the film, featuring a title card that teased its arrival.