Ghana has reported its first fatality from Mpox, marking a concerning milestone as the country faces its most significant weekly surge in cases since the virus was first detected in June 2022. Health authorities confirmed on Sunday that 23 new infections were recorded in the past week alone, raising the total number of cases to 257.

This recent spike has raised fresh alarm, although officials say the situation remains under control.

“The key to limiting this outbreak is early detection and responsible behaviour,” said Health Minister Kwabena Mintah Akandoh, calling for increased vigilance and cooperation from the public.

Mpox — formerly known as Monkeypox — is a viral illness related to smallpox. It typically causes fever, muscle aches, and a distinctive rash with skin lesions. The virus spreads through close contact with infected individuals or contaminated materials, and while most cases are mild, it can lead to severe illness or death.

Vaccination Efforts on the Horizon

Ghana’s public health authorities are preparing to launch a vaccination campaign targeting high-risk groups, with support from the World Health Organization (WHO).

“Our at-risk populations are identified. We’re ready to roll out vaccination once doses arrive,” said Franklyn Asiedu-Bekoe, a senior health official.

Vaccines are expected to be delivered later this week as part of Ghana’s strategy to contain the outbreak and prevent further spread.

A Regional Health Emergency

Ghana’s outbreak reflects a broader resurgence of Mpox across West and Central Africa. Neighboring countries have reported significantly higher caseloads, with Sierra Leone logging over 3,350 cases and 16 deaths in 2025 alone. The Democratic Republic of Congo, Uganda, and Burundi have each reported thousands of additional infections.

The spread of Mpox across the region has raised concerns among public health experts, who warn that underfunded health systems and limited access to vaccines could worsen the crisis.

Public Awareness and Preventive Measures

Authorities are urging the public to remain cautious and informed. Public health campaigns are emphasizing the importance of hygiene, avoiding close contact with symptomatic individuals, and reporting any signs of illness early.

As Ghana braces for a wider rollout of vaccines, officials remain hopeful that swift action and public cooperation will help curb the virus.

Mpox was first identified in humans in the 1970s but has re-emerged in recent years with increased frequency and global spread, prompting the WHO to strengthen international surveillance and response efforts.